Adam Ritchie is a Departmental Lecturer at the Blavatnik School of Government and a Lecturer in Human Science at St Catherine’s College. He coordinates Core IV of the MPP, Science and Public Policy. He was previously based at the Weatherall Institute of Molecular Medicine, University of Oxford, as part of the Centre for HIV/AIDS Vaccine Immunology (CHAVI).
Since moving to Oxford in 2005, Adam has taught for numerous Oxford colleges and international universities, including Stanford and Cornell. He recently received the St Bonaventure University 150th Anniversary Medal for services to education at that institution (July, 2012). Adam completed his undergraduate and DPhil studies at the University of New South Wales, Australia, where he was the awarded the Jackson Prize for Microbiology and Immunology (October, 2000).
Adam’s area of scientific interest is the interaction between infectious organisms and the human host, and he has previously researched areas as diverse as malaria, prions, and the bacterium Pseudomonas aeruginosa. His recent work with CHAVI focused on the role of the immune system in protecting rare individuals who are resistant to HIV infection, and characterizing the immune responses that occur during the earliest stages following HIV infection, and was recognized with the receipt of the CHAVI Young Investigator Award (October, 2010). Adam also carries out research looking into the impact of large-scale scientific studies on intellectual and scientific capacity building in Africa. He has authored numerous scientific journal articles relating to these areas of work.
Adam received a Teaching Excellence Award from the University of Oxford in 2013.
- Ritchie AJ, Plugge E, “Managing student diversity and learning through group formative assessment”, Master Level Teaching, Learning and Assessment.
- Ritchie AJ, Cai F, Smith NMG, Chen S, Song H, Brackenridge S, Karim SSA, Korber B, McMichael AJ, Gao F, Goonetilleke N. 2014. Retrovirology. 14:20-4
Recombination mediates rapid escape from primary CD8+ T cells in acute HIV-1 infection.
- Ritchie AJ, Crawford DM, Ferguson DJP, Burthem J, Roberts DJ, 2013. Brit. J. Haematology 163 (5):678-80
Normal prion protein is express on exosomes isolated from human plasma.
- Pala P, Serwanga J, Watera C, Ritchie AJ, Moodie Z, Wang M, Goonetilleke N, Birabwa E, Hughes P, Senkaali D, Nakiboneka R, Grosskurth H, Haynes B, McMichael A, Kaleebu P, the CHAVI study team and the Centre for HIV/AIDS Vaccine Immunology, 2013. Journal of Virology 87 (16):9053-63
Quantitative and qualitative differences in the T cell response to HIV in uninfected Ugandans exposed or unexposed to HIV infected partners
- Liu MKP, Hawkins N, Ritchie AJ, Ganusov V, Whale V, Brackenridge S, Li H, Pavelick J, Cai F, Rose-Abrahams M, Treurnicht F, Hraber P, Riou C, Gray C, Ferrari G, Tanner R, CHAVI Core B, Cohen M, Karim SSA, Haynes B, Borrow P, Perelson AS, Shaw GM, Hahn BH, Williamson C, Korber BT, Gao F, Self S, McMichael A, Goonetilleke N. 2013. Journal of Clinical Investigation. 123(1):380-93.
Vertical T cell immunodominance and epitope entropy determine HIV-1 escape.
- Ritchie AJ, Kuldanek K, Moodie Z, Wang ZM, Fox J, Nsubuga RN, Legg K, Birabwa EF, Kaleebu P, McMichael AJ, Watera C, Goonetilleke N, Fidler S, 2012. PLoS One. 7(5):e37727.
Comparison of sexual behavior and HIV risk between two HIV-1 serodiscordant couple cohorts: the CHAVI 002 study.
- Ritchie AJ, Campion SL, Kopycinski J, Moodie Z, Wang ZM, Pandya K, Moore S, Liu MK, Brackenridge S, Kuldanek K, Legg K, Cohen MS, Delwart EL, Haynes BF, Fidler S, McMichael AJ, Goonetilleke N, 2011. Journal of Virology. 85 (7), p3507-15.
Differences in HIV-Specific T Cell Responses between HIV-Exposed and -Unexposed HIV-Seronegative Individuals.
- Ritchie AJ, Whittall C, Lazenby JJ, Chhabra SR, Pritchard DI, and Cooley MA, 2007. Immunology and Cell Biol. 85(8) p596-602.
The immunomodulatory Pseudomonas aeruginosa signalling molecule N-(3-oxododecanoyl)-L-homoserine lactone enters mammalian cells in an unregulated fashion.
- Ritchie AJ, Janssen A, Nilsson P, Lysaght PJR, and Cooley MA, 2005. Infection and Immunity 73 (3), p1648-55.
The P. aeruginosa quorum sensing molecule N-(3-oxododecanoyl)-L-homoserine lactone inhibits T cell differentiation and cytokine production by a mechanism involving an early step in activation.
- Ritchie AJ, Yam OW, Tanabe KM, Rice SA, and Cooley MA, 2003. Infection and Immunity 71 (8), p4421-31.
Modification of in vivo and in vitro T- and B-cell-mediated immune responses by the Pseudomonas aeruginosa quorum sensing molecule N-(3-oxododecanoyl)-L-homoserine lactone (OdDHL).